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ClinSCI™

Accelerate Statistical Programming.
Automate TLF Delivery.

Slash SDTM and ADaM creation time, automate TLF generation, and deliver analysis outputs faster with agentic, platform-native statistical programming.

Modern Trials Demand Faster Statistical Delivery

ClinSCI™ embeds AI-driven standardization, agentic TLF generation, and governed programming workflows directly into the ThoughtSphere platform

Smart Map UI Screenshot

AI-driven mapping accelerates SDTM and ADaM standardization with intelligent automation.

AI Smart Mapping

Standardize Faster with AI Smart Mapping

ClinSCI™ uses an Agentic mapping to automate SDTM and ADaM mappings using metadata, NLP, CDISC standards, delivering high out-of-the-box coverage.

Agentic Mapping Capabilities:

  • Agentic mapping for automated SDTM & ADaM conversion
  • Conformance checks to detect invalid or non-standard data early
  • Mapping workbench for review and refinement

Human-in-the-Loop & Traceability:

  • Human-in-the-loop learning to improve future mappings
  • Synthetic test data generation to visualize & test mappings
  • Direct progression into governed ADaM creation workflows
  • Built-in traceability between SDTM and ADaM datasets

This removes fragile custom integrations and makes E2B generation repeatable and scalable across studies.

Smart TLF

Generate TLF Shells With Agentic Automation

ClinSCI™ includes Smart TLF functionality that automates mapping and generation of Tables, Listings, and Figures directly from a reusable library — dramatically reducing manual programming effort.

Smart TLF Capabilities:

  • Library of reusable TLF shells available out of the box
  • Agentic mapping from datasets to TLF structures
  • Drag-and-drop TLF Designer for custom layouts

Smart TLF Capabilities:

  • Approval workflows for TLF definitions
  • Reusable TLF templates across studies and programs

TLF Designer UI Screenshot

TLF generation becomes faster, more repeatable, and less code-heavy without sacrificing flexibility.

Programming Workflow & Submission Package Screenshot

Flexible programming with built-in governance and submission readiness.

Programming & Submission

Programmable, Governed, Analysis-Ready.

ClinSCI™ supports flexible programming while maintaining governance and submission readiness.

Programming Features:

  • Support for R, Python, and SAS
  • Reusable function libraries and utilities
  • Parameter-based analyses and imputations
  • DTYPE mapping tools for record completion

Submission & Workflow Tracking:

  • Submission configuration for validation-ready SDTM & ADaM packages
  • Real-time workflow tracking for dataset creation and approval

Accelerate Statistical Deliverables with Agentic Automation

See how ClinSCI™ helps biostatistics and programming teams standardize faster, generate TLFs automatically, and deliver submission-ready outputs with confidence.